Stem Cells as Potential Candidates for Psoriasis Cell-Replacement Therapy

Psoriasis is a chronic disease affecting over 125 million people all over the world and an increasing trend has been observed [1,2]. As a systemic inflammatory process, it predisposes, twice as frequently than in the general population, to the development of metabolic disorders (insulin resistance, atherogenic dyslipidemia, arterial hypertension, and cardio-vascular diseases) and, consequently, to [...]

Mesenchymal Stem Cell Therapy for Inflammatory Skin Diseases: Clinical Potential and Mode of Action

Inflammatory skin diseases such as atopic dermatitis (AD) and psoriasis are considered major public issues with increasing prevalence due to the rapid industrialization of modern society. These diseases are more frequent in industrialized countries than in developing countries with higher prevalence in urban areas compared to rural areas. [pdf-embedder url="" title="MSC's in Inflammatory Skin Diseases [...]

Three-week topical treatment with placenta – derived mesenchymal stem cells hydrogel in a patient with diabetic foot ulcer

The International Diabetes Federation reported that, at present, there are 415 million subjects worldwide with diabetes mellitus (DM) aged between 20 and 79 years, with a global prevalence of 8.8%, which by 2030 will increase to >360 million. [pdf-embedder url="" title="MSC's (topical) in the Tx of Diabetic Foot Ulcer Dec 2017"]

The Use of Adipose-Derived Stem Cells in Selected Skin Diseases (Vitiligo, Alopecia , and Non-healing Wounds)

Brown and white adipose tissue is a source of mesenchymal stem cells, specifically adipose-derived stem cells (ADSCs). It is an inexpensive, unlimited reservoir of stem cells. From 300 ml of adipose tissue, 2-3 × 108 ADSCs can be obtained. [pdf-embedder url="" title="ADSC's in Vitiligo, Alopecia & Wounds Aug 2017"]