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Anterior cruciate ligament reconstruction (ACLR) has been established as the gold standard for treatment of complete ruptures of the anterior cruciate ligament (ACL) in active, symptomatic individuals. In contrast, treatment of partial tears of the ACL remains controversial. Biologically augmented ACL-repair techniques are expanding in an attempt to regenerate and improve healing and outcomes of [...]
Articular cartilage is a hyaline lining on the articular surface of bone ends. It cushions external impacts and reduces friction between bones to enable smooth and painless joint motion. Chondrocytes are the only resident cell type in cartilage and comprise 1–5% of articular cartilage. These cells produce collagen, proteoglycans, and hyaluronic acid, which are components [...]
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide, with acute myocardial infarction (AMI) representing the most common CVD. Coronary artery disease (CAD) resulting in myocardial infarction (MI) can lead to ischemic heart damage, which, depending on the ability and timing of reperfusion, may be reversible or irreversible. Cardiomyocytes depend on constant [...]
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide, with acute myocardial infarction (AMI) representing the most common CVD. Coronary artery disease (CAD) resulting in myocardial infarction (MI) can lead to ischemic heart damage, which, depending on the ability and timing of reperfusion, may be reversible or irreversible. Cardiomyocytes depend on constant [...]