Cellular therapy with human autologous adipose-derived adult cells of stromal vascular fraction for alopecia areata

Most common forms of hair loss (alopecia) are caused by aberrant hair follicle cycling and changes in hair follicle morphology. However, current treatments for alopecia do not specifically target these processes. Adipose-derived stromal vascular cells (ADSVCs) that can be harvested from fat cells are one of the latest breakthroughs in the aesthetic field.

Stem Cells in Tx Alopecia May 2018
By |2018-07-16T17:42:33+00:00July 16th, 2018|Alopecia, Hair Restoration, Hearing Loss|Comments Off on Cellular therapy with human autologous adipose-derived adult cells of stromal vascular fraction for alopecia areata

A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification

Platelet-rich plasma (PRP) is currently used in different medical fields. The interest in the application of PRP in dermatology has recently increased. It is being used in several different applications as in tissue regeneration, wound healing, scar revision, skin rejuvenating effects, and alopecia.

PRP History, Biology Mechanism July 2017
By |2018-07-16T17:32:13+00:00July 16th, 2018|Alopecia, Platelet Rich Plasma – PRP, Skin Rejuvenation|Comments Off on A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification

The Use of Adipose-Derived Stem Cells in Selected Skin Diseases (Vitiligo, Alopecia , and Non-healing Wounds)

Brown and white adipose tissue is a source of mesenchymal stem cells, specifically adipose-derived stem cells (ADSCs). It is an inexpensive, unlimited reservoir of stem cells. From
300 ml of adipose tissue, 2-3 × 108 ADSCs can be obtained.

ADSC's in Vitiligo, Alopecia & Wounds Aug 2017
By |2018-07-16T12:55:13+00:00July 16th, 2018|Adipose Tissue, Alopecia, Non Healing Wounds, Skin Diseases, Skin Rejuvenation, Stem Cells|Comments Off on The Use of Adipose-Derived Stem Cells in Selected Skin Diseases (Vitiligo, Alopecia , and Non-healing Wounds)

Platelet-rich plasma—an ‘Elixir’ for treatment of alopecia: personal experience on 117 patients with review of literature

Platelet-rich plasma (PRP) has emerged as a new treatment modality in regenerative plastic surgery and dermatology. PRP is a simple, cost-effective and feasible treatment option with high patient satisfaction for hair loss and can be regarded as a valuable adjuvant treatment modality for androgenic alopecia and other types of non-scarring alopecias. Authors have proposed a hair model termed “Golden anchorage with ‘molecular locking’ of ectodermal and mesenchymal components for survival and integrity of hair follicle (HF)” in this article. Golden anchorage comprises of bulge stem cells, ectodermal basement membrane and bulge portion of APM. PRP with its autologous supply of millions of growth factors works on ‘Golden anchorage’ along with keratinocytes (PDGF), dermal papilla (IGF and firoblast growth factor), vasculature (VEGF and PDGF) and neural cells (Nerve Growth Factor) in a multipronged manner serving as an ‘elixir’ for hair growth and improving overall environment.

PRP in Alopecia 117 patients
By |2018-07-16T11:11:18+00:00July 16th, 2018|Alopecia, Stem Cells|Comments Off on Platelet-rich plasma—an ‘Elixir’ for treatment of alopecia: personal experience on 117 patients with review of literature

The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial

Platelet-rich plasma (PRP) has emerged as a new treatment modality in regenerative plastic surgery, and preliminary evidence suggests that it might have a beneficial role in hair regrowth. Here, we report the results of a randomized, evaluator-blinded, placebo-controlled, half-head group study to compare, with the aid of computerized trichograms, hair regrowth with PRP versus placebo. The safety and clinical efficacy of autologous PRP injections for pattern hair loss were investigated. PRP, prepared from a small volume of blood, was injected on half of the selected patients’ scalps with pattern hair loss. The other half was treated with placebo.

The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial
By |2018-07-16T09:56:11+00:00July 16th, 2018|Alopecia, Hair Restoration, Platelet Rich Plasma – PRP|Comments Off on The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial