What is Ankle instability?

Ankle sprains are noted to be one of the most common musculoskeletal treatments that are treated. Chronic ankle instability develops after repeated ankle sprains. It is a condition that incorporates persistent pain, recurrent sprains and repeated instances of giving away, which may lead to osteoarthritis. Giving away usually occurs while walking or doing other physical activities. Muscle weakness, static alignment, ligamentous injury and poor proprioception contribute to this condition. If untreated, ankle instability decreases someone’s level of body functionality and quality of life. It may lead to arthritis and chronic pain.




Causes & Symptoms

An ankle sprain occurs when one’s foot is twisted inward. If the sprain does not adequately heal and is not rehabilitated correctly, it may be stretched into a lengthened position and end up healing that way. When the ankle is sprained, the ligaments are stretched or torn, and have to undergo proper rehabilitation needed to strengthen the muscles around the ankle. Failure to do so increases the risk of chronic ankle instability because of repeated ankle sprains. With each subsequent sprain, ligaments are weakened further or stretched, which worsens instability and the likelihood of developing added problems in the ankle, such as osteoarthritis.

One of the major symptoms of this condition is instability of the ankle. One is not able to put weight on their foot without always fearing that the ankle will roll. It is also characterized by persistent discomfort and swelling, pain or tenderness and repeated turning of the ankle.




One of the options for ankle instability is Platelet Rich Plasma. It involves the introduction of a high concentration of platelets that catalyze the platelets to begin the process of healing by increasing blood flow. The patient’s blood is drawn from the arm then placed into a centrifuge so as to obtain the highest concentration of platelets available. The ligament area is anesthetized, and PRP is delivered by injection to the ankle ligaments. Most times, a walking boot is prescribed to control the stress on the ligaments when healing. A second or third PRP therapy may benefit some patients depending on their progress.

How is this condition treated with stem cell therapy
(Regenerative Therapies)?

A crucial role is played by mesenchymal stem cells in the repair of ankle degeneration. This is because they have:

  • Immunomodulatory peculiarities. They change the joint to a healing environment from a diseased one.

  • Regenerative properties. They restore the bone and cartilage tissue.

  • Properties that regulate inflammation

Patients who were treated with bone marrow stem cell therapy injections, repaired significantly faster while physicians claim long term benefits.